The aim of this paper is to consider the possibilities for carrying out entrepreneurial activities in Varaždin County. This is achieved by theoretically considering terms entrepreneurship and enterprise, but also by observing the entrepreneurial potential through the pre-conditions necessary for the emergence of entrepreneurship and available entrepreneurial resources such as sources of funding, business support institutions and enterprise zones. Reviewed is also the institutional framework important for entrepreneurial activity and analyzed is entrepreneurial activity in the Republic of Croatia. Special emphasis in this paper is given to the Varaždin County. Presented are geographic, demographic and economic characteristics of the Varaždin County, analyzed is the competitiveness of Varaždin County compared to other counties, the content of Development Strategy of Varaždin County and briefly analyzed certain industries relevant to Varaždin County. In order to gain additional insights into opportunities for entrepreneurial activity, presented are also the benefits offered to the investors.