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Preparation methods of porous scaffolds for biomedical applications
Marija Posarić (2015)
University of Zagreb
Faculty of Chemical Engineering and Technology
Metadata
TitleMetode priprave poroznih skeleta za biomedicinske primjene
AuthorMarija Posarić
Mentor(s)Marica Ivanković (thesis advisor)
Abstract
Cilj ovog rada je dati kratki literaturni pregled metoda priprave poroznih skeleta koji se koriste u području inženjerstva tkiva. Inženjerstvo tkiva je interdiscplinarno područje u nastajanju koje primjenjuje načela prirodnih znanosti i inženjerstva za proizvodnju inženjerskog tkiva za popravak i zamjenu oštećenih tkiva i organa. U inženjerstvu tkiva glavnu ulogu imaju skeleti. Skeleti su trodimenzijske strukture napravljene od bioloških materijala i biomaterijala, koji ispunjavaju osnovne zahtjeve za vezanje i rast stanica. Skeleti napravljeni od polimera, keramike ili kompozita moraju posjedovati specifične karakteristike kao što su visoka poroznost, velika specifična površina, strukturna čvrstoća, specifični trodimenzijski oblik, biokompatibilnost i biorazgradivost. U radu su izdvojene četiri uspješne metode izrade visoko poroznih polimernih i kompozitnih skeleta: elektropredenje, liofilizacija, ispiranje čestica porogena i toplinski potaknuto razdvajanje faza. Svaka od metoda ima jedinstvene prednosti u proizvodnji skeleta za inženjerstvo tkiva.
Keywordsscaffolds tissue engineering porosity
Parallel title (English)Preparation methods of porous scaffolds for biomedical applications
Committee MembersMarica Ivanković (committee chairperson)
Jelena Macan (committee member)
Dajana Milovac (committee member)
GranterUniversity of Zagreb
Faculty of Chemical Engineering and Technology
PlaceZagreb
StateCroatia
Scientific field, discipline, subdisciplineTECHNICAL SCIENCES
Basic Technical Sciences
Materials
Study programme typeuniversity
Study levelundergraduate
Study programmeMaterials Science and Engineering - Undergraduate study
Academic title abbreviationuniv.bacc.ing.cheming.
Genreundergraduate thesis
Language Croatian
Defense date2015-09-03
Parallel abstract (English)
The aim of this work is to give a brief literature review of methods for preparing porous scaffolds used in tissue engineering. Tissue engineering is an interdisciplinary field that applies the principles of life science and engineering to produce engineered tissues for the repair and replacement of damaged tissues or organs. In tissue engineering, scaffolds play a crucial role. Scaffolds are three-dimensional structures made from biological materials and biomaterials, which fulfil the necessary requirements for cell attachment and growth. Scaffolds made of polymers, ceramics or composites; have to possess specific characteristics such as high porosity, high surface area, three-dimensional shape, biocompatibility and biodegradability. In this work, four successful methods for highly porous polymer and composite scaffold preparation are pointed out: electrospinning, freeze-drying, particulate leaching and thermally induced phase separation. Each method has unique advantages in the production of scaffolds for tissue engineering.
Parallel keywords (Croatian)skelet inženjerstvo tkiva poroznost
Resource typetext
Access conditionOpen access
Terms of usehttp://rightsstatements.org/vocab/InC/1.0/
URN:NBNhttps://urn.nsk.hr/urn:nbn:hr:149:280454
CommitterGoran Galinec